Devoted to diagnostic and interventional spine imaging and therapeutics


Radiofrequency Ablation and Sacroplasty in the Treatment of Neoplastic Osteolytic Sacral Localizations 2009

Interventional Spine

Francesco Massari, MD,
Giovanni Simonetti, MD, Non ASSR Member
Roberto Fiori, MD, Non ASSR Member
Dario A Bartolucci, MD, Non ASSR Member
Matteo Mammucari, MD, Non ASSR Member
Salvatore Masala, PhD, ASSR Member

Scientific Paper

Mentor Award: No

Institution where work was conducted

University of Rome “Tor Vergata”, Rome, Italy

Affiliation and Department

Department of Diagnostic and Molecular Imaging, Interventional Radiology and Radiation Therapy


81 Oxford Street
Rome, Alabama
Phone: +39 (339) 2488654


Metastatic cancer is the most common malignant disease of the skeletal system. Traditionally, conventional fractionated external beam radiotherapy has been the treatment of choice. Recently minimally invasive surgical techniques (MISS) have been added to the therapeutic armamentarium. The purpose of our study was to assess the effectiveness and safety of Radiofrequency Ablation and Sacroplasty in the treatment of neoplastic sacral osteolytic localization. The aim of radiofrequency heat ablation is to destroy the tumor tissue before bone stabilization through intralesional injection of cement.

Methods & Materials

We treated 11 patients (Primary neoplasties: 4 Pt lung, 3 prostate, 3 breast, 1 kidney).with unremitting pain over spine and/or in pelvic region, in absence of symptomatic roots compression and refractory to conventional therapeutic options such as radiation therapy, chemotherapy, surgery and use of analgesics.


The method demonstrated swift pain relief (average of 8.4 points of VAS pre-procedure to 2.4 post-procedure), associated with an evident augmentation in bone resistance, in absence of periprocedural complications.


The association of Radiofrequency Heat Ablation and Sacroplasty is an effective, simple and safe treatment of neoplastic vertebral compressive fractures and pelvic osteolytic lesions.