Devoted to diagnostic and interventional spine imaging and therapeutics


Cobb Syndrome: Clinical Features and Imaging Findings 2014

Category General Spine Alok A. Bhatt Norbert Campeau Peter Kalina Purpose Cobb syndrome, also known as cutaneous vertebral medullary angiomatosis, is a disease process which is present at birth, but does not usually present itself until later in life when the patient has numbness or weakness in the extremities. Cutaneous vascular lesions can lead one to image for a spinal angioma or AVM in the same dermatome, with early recognition and intervention proving beneficial. The objectives of this educational exhibit is to review the pathophysiology and imaging findings of Cobb syndrome using a case which presented at our institution. Key learning points: (1) patient demographics, (2) pathophysiology of Cobb syndrome, specifically that it is involves a metameric vascular malformation, involving all 3 embryonal layers, (3) spectrum of physical and imaging findings, (4) complications of Cobb syndrome, including Foix-Alajouanine disease, (5) treatment options. Materials & Methods N/A. Results N/A. Conclusion N/A. References N/A.