Devoted to diagnostic and interventional spine imaging and therapeutics

Library

Efficacy of Discogel® – Radiopaque gelified ethanol + etilcellulose in the treatment of contained disc herniations: a preliminary experience 2012

Interventional Spine

STEFANO, MARCIA, MD
MATTEO, BELLINI, MD, Non ASSR Member
EMANUELE, PIRAS, MD, Non ASSR Member
STEFANO, MARINI, MD, Non ASSR Member
MARIANGELA, MARRAS, MD, Non ASSR Member

Paper/Non-Mentor

Purpose

All the percutaneous procedures for the treatment of painful disc herniations, while having high success rates, result in a reduction of the volume of the intervertebral disc; this may cause an increase in degenerative disease at the same level. The aim of this study is to provide the efficacy of Discogel® - Radiopaque gelified ethanol + etilcellulose (Gelscom®, France) in the treatment of disc protrusions by means of pain relief and maintaining the height of the intervertebral disc.

Methods & Materials

Thirty-three patients (18Male, 15Female, Av. age) with lombosciatic pain due to contained disc herniations were selected for treatment with injection of Discogel. Diagnosis was confirmed by MRI in all patients. All procedures were performed under fluoroscopic guidance and with local anesthesia. Twenty-two gauge needles were used and 8ml of ethanol gel + etilcellulose were injected for each intervertebral disc. Clinical evaluation, assessment of pain by mean of a 11-points visual analogue scale (VAS, 0-10) and of function by means of the Oswestry disability scale(ODI 0-50) was performed at baseline and at one month after the procedure. CTms checks has been performed immediately after the procedure and at one month. The volume was calculated with Advantage viewer system (GE, UK).

Results

A total of 37 intervertebral discs were treated in the 33 patients enrolled in the study. Baseline pain was ± , baseline ODI was 36.1 ± 10.4. At one month, pain was ± , while ODI was 16.5 ± 2.8(p<0.01). We reported an increase of 41.9% in the volume of the intervertebral disc (Av. Volume before: 8.07, after: 11.4cm3). We reported one asymptomatic canal leakage.

Conclusion

From our preliminary study, the injection of Discogel® is an optimal therapy for symptomatic patients with contained disc herniations. Furthermore the etilcellulose, through the formation of a soft prosthesis, ensures the manteinance of disc height.

[gallery]